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Target intelligence / Profile preview
SMIM15 antisense RNA 1 (SMIM15-AS1)
- Target
- SMIM15-AS1
- Molecular classification
- Non-coding RNA (ncRNA), Antisense RNA, Other
01
Overview
SMIM15 antisense RNA 1 (SMIM15-AS1) is a long non-coding antisense RNA gene annotated at locus 5q12.1, transcribed antisense to the SMIM15 protein-coding gene. It is classified as a non-coding RNA and possesses alternative alias CTC-436P18.1. SMIM15-AS1 has been investigated in transcriptomics and RNA editing studies, including analysis of A-to-I RNA editing events in Alzheimer’s disease samples, which may alter RNA transcript stability or function, though its biological significance and molecular function are currently unknown. SMIM15-AS1 is not considered a therapeutic target or validated disease gene, and no drugs, biomarkers, or safety concerns have been documented for it.
- Other names
- CTC-436P18.1
02
Biological functions
No well-defined or validated biological function in the literature; potential involvement in RNA stability or regulation due to observed RNA editing events
03
Disease associations
No direct, validated roles in diseaseAssociated with differential gene expression and RNA A-to-I editing in Alzheimer's disease research datasets, but functional or pathogenic significance is unproven
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