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Target intelligence / Profile preview
SMS pseudogene 1 (SMSP1)
- Target
- SMSP1
- Molecular classification
- Pseudogene
01
Overview
SMS pseudogene 1 (SMSP1) is a genomic sequence related to the Spermine synthase (SMS) gene but has been rendered non-coding by mutations or regulatory loss. Pseudogenes such as SMSP1 do not produce a functional protein and are typically regarded as non-functional genetic elements. However, some pseudogenes can exert regulatory effects on their parent genes—such as altering mRNA stability, acting as competing endogenous RNAs, or contributing to genetic diversity through recombinational events. To date, there is no evidence that SMSP1 has a direct role in disease, functions as a therapeutic target, or is associated with recognized biomarkers or interacting drugs.
02
Mechanism of action
None applicable for drugs; pseudogenes are not protein targets but may impact disease indirectly via gene regulation
03
Biological functions
Regulation of gene expression via miRNA competitionGeneration of long non-coding RNAs (lncRNAs) that regulate nearby genesPotential recombination with parental gene leading to genetic diversity
04
Disease associations
No direct disease roles attributed to SMSP1
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