SMT3 suppressor of mif two 3 homolog 2, pseudogene

ENSG00000267800 corresponds to a **pseudogene** of the SMT3 suppressor of mif two 3 homolog 2 (SUMO2) gene rather than to a functional protein-coding gene or direct therapeutic target[4]. Pseudogenes are non-functional genomic DNA sequences similar to known genes but typically do not produce active proteins. The true gene, SUMO2 (small ubiquitin-like modifier 2), is a member of the SUMO protein family involved in post-translational modification of other proteins and diverse cellular processes such as nuclear transport and regulation of transcription[1][3][6]. However, as a pseudogene, ENSG00000267800 does not encode a functional protein and has no established therapeutic, biological, or disease role. **Clarification:** There is a functional gene, **SUMO2** (small ubiquitin-like modifier 2), which is often studied for its cellular and disease relevance, but ENSG00000267800 specifically refers to a **pseudogene** version, which is not an active drug target[4]. If you seek information on the active SUMO2 protein, use the entry ENSG00000188612 instead[3]. **Summary of issues:** - ENSG00000267800 is a pseudogene and not a functional molecule of therapeutic interest[4]. - It is not considered a valid drug target, nor does it have known protein, disease, or drug associations. - Any search for functional data should use the canonical SUMO2 gene rather than its pseudogene counterpart.

Other names

SMT3 suppressor of mif two 3 homolog 2, pseudogeneSUMO2 pseudogeneSMT3H2 pseudogenesmall ubiquitin-like modifier 2 pseudogeneENSG00000267800