Target intelligence / Profile preview

Sodium gluconate

Molecular classification
Organic acid salt, Chelating agent, Electrolyte
01

Overview

Sodium gluconate is the sodium salt of gluconic acid, typically produced through the fermentation of glucose (PubChem CID 23672301). In clinical settings, it is not a therapeutic target such as a receptor or enzyme, but rather a component of intravenous replacement fluids used to manage electrolyte imbalances and metabolic acidosis (DailyMed, Plasma-Lyte 148). Upon administration, it undergoes metabolic oxidation to generate bicarbonate, which serves as a systemic alkalizer (NIH, LiverTox). Additionally, sodium gluconate is a highly effective chelating agent, capable of sequestering metal ions like calcium and iron in various environments (ScienceDirect). Its primary role in medicine is to support physiological homeostasis rather than to modulate a specific signaling pathway.

Other names
D-Gluconic acid monosodium saltSodium D-gluconateGluconic acid sodium salt
02

Mechanism of action

Acts as an electrolyte replenisher and a metabolic precursor to bicarbonate; it is oxidized in the body to provide an alkalizing effect and helps maintain osmotic pressure.

03

Biological functions

Electrolyte balanceAcid-base bufferingMetal ion chelation
04

Disease associations

HyponatremiaMetabolic acidosisDehydration
05

Safety considerations

HypernatremiaFluid retentionMetabolic alkalosis
06

Interacting drugs

Plasma-Lyte 148

2 more in the full profile.

07

Biomarkers

Serum sodium levelsBlood pHSerum bicarbonate

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