Solute carrier family 12 member 9 (SLC12A9)

SLC12A9 (Solute carrier family 12 member 9) encodes a protein that is a putative member of the cation-chloride cotransporter family, functioning as a transporter involved in potassium and chloride ion homeostasis and transmembrane transport[1][2][3][5]. Although the exact physiological role remains unclear, evidence suggests involvement in lysosomal ion flux and osmoregulation[2]. Genome-wide association studies have implicated SLC12A9 in cardiac function through genetic association with resting heart rate, while altered expression is linked to poor prognosis in certain cancers, such as uveal melanoma and colorectal cancer[1]. SLC12A9 is considered a transporter protein and a potential emerging therapeutic and prognostic target in disease[1][2].

Other names

CCC6CIP1hCCC6WO3.3cation-chloride cotransporter 6cation-chloride cotransporter-interacting protein 1potassium-chloride transporter 9solute carrier family 12 (potassium/chloride transporters), member 9