Solute carrier family 16 member 13 (SLC16A13 (also MCT13))

Solute carrier family 16 member 13 (SLC16A13, also known as monocarboxylate transporter 13 or MCT13) is a proton-linked transporter belonging to the SLC16 family of monocarboxylate transporters, responsible for transporting monocarboxylic acids such as lactate across cellular membranes[5][7]. It is an orphan transporter, meaning its full substrate profile and physiological functions are not completely characterized[6]. SLC16A13 is expressed in human tissues including the Golgi apparatus and cytosol, and is implicated in energy metabolism, particularly related to glucose and lipid regulation[2][4]. Genetic studies have linked SLC16A13 variants to increased susceptibility for type 2 diabetes and hepatic steatosis through effects on hepatic insulin sensitivity and lipid accumulation[2]. There are currently no established drugs directly targeting this transporter, and its precise role in disease and therapy remains under investigation[2][5][6][7].

Other names

Monocarboxylate transporter 13MCT13MOT13_HUMAN

Proton-linked transport of monocarboxylates (e.g., lactate, possibly others) across plasma membrane