Solute Carrier Family 2 Facilitated Glucose Transporter Member 2 (GLUT2)

Solute carrier family 2 facilitated glucose transporter member 2 (SLC2A2 / GLUT2) is a transmembrane carrier protein that enables the facilitated movement of glucose and other hexoses across cell membranes. It plays a vital role in glucose homeostasis, particularly in the liver, pancreatic beta cells, small intestine, and kidneys. GLUT2 has a low affinity but high capacity for glucose, allowing for bidirectional transport based on concentration gradients. Mutations or altered expression are associated with diseases like Fanconi-Bickel Syndrome and Type II Diabetes Mellitus.

Other names

SLC2A2GLUT-2Glucose transporter type 2

Facilitated diffusion of glucose and other hexoses across cell membranes