Target intelligence / Profile preview

Solute Carrier Family 2 Facilitated Glucose Transporter Member 4 (GLUT4)

Target: GLUT4
Molecular classification: Transporter, Solute Carrier Family, Facilitated Glucose Transporter

Overview

Solute carrier family 2 facilitated glucose transporter member 4 (GLUT4), encoded by the SLC2A4 gene, is an insulin-regulated glucose transporter primarily found in adipose tissue and striated muscle. It facilitates glucose diffusion into cells, playing a key role in removing glucose from circulation and maintaining whole-body glucose homeostasis. GLUT4's unique trafficking capabilities, regulated by insulin, make it a crucial target for understanding and treating metabolic disorders like diabetes and obesity.

Other names: SLC2A4

Biological functions

Glucose transportInsulin-regulated glucose uptakeGlucose homeostasis

Disease associations

ObesityDiabetesInsulin resistanceMetabolic syndrome

Beyond the preview

Go deeper on Solute Carrier Family 2 Facilitated Glucose Transporter Member 4 (GLUT4).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Solute Carrier Family 2 Facilitated Glucose Transporter Member 4 (GLUT4).

Explore the full profile