Target intelligence / Profile preview

Solute carrier family 22 member 1, 2, and 3 (Organic cation transporter 1, 2, and 3) (OCT1-3)

Target
OCT1-3
Molecular classification
Transporter, Solute carrier family
01

Overview

Other names
SLC22A1SLC22A2SLC22A3hOCT1hOCT2hOCT3Organic cation transporter 1Organic cation transporter 2Organic cation transporter 3EMTUptake2Extraneuronal monoamine transporter
02

Biological functions

Transport of organic cationsDrug dispositionNeurotransmitter transportMetabolic homeostasisThiamine transport
03

Disease associations

Type 2 diabetesCancerCardiovascular diseaseNeurodegenerative diseaseCholestasis
04

Interacting drugs

Metformin

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