Solute carrier family 22 member 3 pseudogene

Solute carrier family 22, member 3 pseudogene (ENSG00000276960) refers to a predicted or annotated pseudogene related to the functional SLC22A3 gene, which encodes the organic cation transporter 3 (OCT3)[1][2]. However, this specific ENSG00000276960 entry represents a non-functional sequence that does not produce a functional transporter protein. Pseudogenes can arise from duplication or retrotransposition events and lack the capacity to encode functional proteins—often due to disruptive mutations, deletions, or lack of necessary regulatory regions. Thus, ENSG00000276960 is not considered a therapeutic target and has no documented drug interactions, biological functions, or clinical relevance as a protein-coding entity. Important clarification: - SLC22A3, alias "organic cation transporter 3 (OCT3)," is a well-characterized transporter and bona fide drug target involved in neurotransmitter and drug transport[1][2]. - ENSG00000276960, in contrast, is a pseudogene and should not be confused with the functional SLC22A3 protein. If you require information on the active transporter (OCT3, SLC22A3) instead of the pseudogene, please specify—otherwise, the above applies to ENSG00000276960.