Solute carrier family 22 member 31 (SLC22A31)

SLC22A31 is a putative member of the solute carrier family 22, a large group of membrane-bound transporters involved primarily in the movement of ions, organic cations and anions, and endogenous metabolites across cell membranes[3][4]. The SLC22 transporter family is subdivided into several subfamilies such as organic anion transporters (OAT), organic cation transporters (OCT), and related groups, with SLC22A31 classified as an *OAT-related* orphan transporter[3]. While the function of most SLC22 family members is well characterized, SLC22A31 remains poorly understood, with only predictions of its role in ion and small molecule transport based on its sequence homology and membrane localization[2][3]. SLC22A31 is expressed in tissue such as the larynx and prostate, but specific physiological substrates, regulatory mechanisms, and clinical relevance are yet to be elucidated[3]. Disease association has been suggested with KBG syndrome; further research is required to validate its role as a drug target or clinical biomarker[2].

Other names

Putative solute carrier family 22 member 31SLC22A31ENSG00000182157HGNC: 27091NCBI Gene: 146429UniProt: A6NKX4

Not defined for SLC22A31 (mechanisms for related SLC22 transporters include organic anion/cation transport, driving absorption/excretion of drugs and metabolites)