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Target intelligence / Profile preview
Solute carrier family 23 member 2 (SLC23A2)
- Target
- SLC23A2
- Molecular classification
- Transporter, Solute Carrier Family
01
Overview
SLC23A2 is a sodium-dependent vitamin C transporter responsible for the uptake of ascorbate into cells. It plays a critical role in tissue-specific vitamin C distribution, particularly in the brain, placenta, and other tissues. Deficiency in SLC23A2 can lead to reduced neuronal function, increased susceptibility to oxidative damage, and impaired collagen stability.
- Other names
- Na(+)/L-ascorbic acid transporter 2Nucleobase transporter-like 1 proteinSodium-dependent vitamin C transporter 2hSVCT2Yolk sac permease-like molecule 2NBTL1YSPL2
02
Mechanism of action
Sodium/ascorbate cotransport
03
Biological functions
Vitamin C transportAscorbate uptakeNeurotransmission supportAntioxidant defenseNutrient transport
04
Disease associations
Neurological development disordersPlacental/fetal health issuesConnective tissue disordersOxidative stress-related diseases
05
Safety considerations
Potential impact on collagen synthesis/stabilityNeurological effects from deficiencyFetal development concerns
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