Solute carrier family 25 member 34 (SLC25A34)

Solute carrier family 25 member 34 (SLC25A34) is a protein localized to the inner mitochondrial membrane and is a member of the mitochondrial carrier SLC25 family[1][6][7]. It functions as a putative antiporter, presumably exchanging dicarboxylates and sulfur oxoanions across the mitochondrial inner membrane, and may contribute to intracellular metabolite exchange and energy homeostasis[3][6]. While SLC25A34 shares homology with other functionally characterized mitochondrial transporters, its specific substrates and biological roles remain poorly characterized, and there is limited direct evidence linking it to particular physiological or pathological conditions[5][7]. The SLC25 family as a whole is essential for mitochondrial metabolism, transporting various metabolites, nucleotides, and co-factors, and some members have established roles in cancer metabolism, apoptosis, and metabolic homeostasis; however, SLC25A34 itself is currently under-characterized, with no direct links to drug interactions, biomarker status, or specific disease mechanisms in the available literature[2][5][6][7].

Other names

SLC25A34DKFZp781A10161S2534_HUMAN