Target intelligence / Profile preview

Solute carrier family 25 member 35 (SLC25A35)

Target
SLC25A35
Molecular classification
Transporter, Mitochondrial carrier, Solute carrier
01

Overview

Solute carrier family 25 member 35 (SLC25A35) is a mitochondrial carrier protein belonging to the SLC25 family, which functions as a transporter of metabolites across the inner mitochondrial membrane[3][5]. Like other SLC25 family members, it is thought to play important roles in mitochondrial metabolite exchange, energy production, and cellular metabolism[2][3]. SLC25A35 is a protein-coding gene expressed in various tissues, but its specific substrate(s) and transport mechanism remain poorly characterized compared to other family members. Alterations in SLC25A35 have been linked to dilated cardiomyopathy, suggesting a role in cardiac metabolic health[5]. No drugs or specific targeting mechanisms are currently known for SLC25A35, and there are no established biomarkers or safety concerns directly attributed to its inhibition or modulation.

Other names
SLC25A35FLJ40217
02

Biological functions

Mitochondrial metabolite transportCellular metabolismInner mitochondrial membrane transport
03

Disease associations

Dilated cardiomyopathyOther (rare/less characterized human diseases)

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