Solute carrier family 35 member E2B (SLC35E2B)

The "novel transcript, antisense to SLC35E2B" (ENSG00000272004) refers to a putative noncoding RNA transcribed opposite the SLC35E2B gene locus. There is no direct evidence that this transcript encodes a protein, is involved in disease, or plays a defined biological role. The canonical gene at this locus is SLC35E2B, which encodes a predicted membrane-bound transporter protein in the nucleoside-sugar transporter family (SLC35). SLC35E2B is predicted to function as an antiporter involved in transmembrane transport within the Golgi apparatus, with possible roles in membrane nutrient/metabolite exchange and development (blastocyst hatching). SLC35E2B is weakly implicated in myopia but is not broadly associated with other diseases, drugs, or therapeutic mechanisms[2][3][1]. No drugs, biomarkers, or safety concerns are documented for either the antisense transcript or SLC35E2B.

Other names

Solute carrier family 35 member E2BSLC35E2BENSG00000189339 (canonical SLC35E2B gene)HGNC:33941 (SLC35E2B)NCBI Gene:728661 (SLC35E2B)OMIM:619315 (SLC35E2B)UniProtKB:P0CK96 (SLC35E2B)S352B (by some databases)

Not defined for the antisense transcript. For SLC transporters generally: secondary active or facilitative transport mechanisms using chemical gradients.