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Target intelligence / Profile preview
Solute carrier family 35 member F5 (SLC35F5)
- Target
- SLC35F5
- Molecular classification
- Transporter, Membrane protein, Solute carrier (SLC), family 35, Nucleotide-sugar transmembrane transporter (predicted)
01
Overview
Solute carrier family 35 member F5 (SLC35F5) is a predicted membrane-bound putative solute transporter, likely involved in the transmembrane transport of nucleotide sugars or related metabolites, as inferred by homology to other SLC35 family members. It shows expression across various tissues and may have a role in cellular metabolism or glycosylation. Although associated with certain rare inherited disorders (Seckel syndrome, Fanconi anemia), its precise physiological function and disease mechanisms remain poorly characterized. No drugs or clinical interventions are currently directed at SLC35F5, and there is no evidence that it serves as a biomarker or has unique safety liabilities.
- Other names
- NS5ATP3UNQ2545/PRO6097HCV NS5A-transactivated protein 3FLJ22004Hepatitis C virus NS5A-transactivated protein 3solute carrier family 35 member F5
02
Biological functions
Putative nucleoside/nucleotide-sugar transport across membranesLikely involved in metabolism of nucleotide sugars and possibly glycosylation, as with other SLC35 family membersPossible role in cell proliferation (as inferred from SLC35 family G2 member interactions)
03
Disease associations
Seckel syndromeFanconi anemia, Complementation Group A (association via genetic studies; mechanistic link unclear)
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