Solute carrier family 36 pseudogene

ENSG00000253897 is annotated as a **pseudogene** related to the solute carrier family 36 (SLC36). Pseudogenes are noncoding genomic DNA sequences that resemble known genes but are non-functional due to mutations, deletions, or insertions, preventing them from producing functional proteins. As such, this locus is not a functional transporter, receptor, enzyme, or any class of bona fide therapeutic target. It should not be considered a candidate for drug discovery or biomarker development. The "solute carrier" (SLC) family, in general, comprises transporter proteins involved in the transmembrane movement of various solutes, but a pseudogene does not encode a functional protein capable of transporter activity[2][3][4][6]. **Clarification:** - This gene entry encodes a **pseudogene**, not a functional member of SLC36 (such as SLC36A1 or SLC36A4, which are true amino acid transporters)[1][5]. - Pseudogenes are not valid targets for therapeutic intervention and generally have no known biological function or disease role. - The presence of "solute carrier family 36" in the name reflects sequence similarity, not function—no transmembrane transporter is produced. If additional therapeutic, biological, or pharmacological information is required, it is necessary to refer to a protein-coding SLC36 family gene such as **Solute carrier family 36 member 1 (SLC36A1, ENSG00000123643)** or **Solute carrier family 36 member 4 (SLC36A4, ENSG00000180773)**[1][5].

Other names

SLC36 pseudogenesolute carrier family 36 pseudogeneENSG00000253897