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Solute carrier family 39 (zinc transporter), member 14 pseudogene (ENSG00000227236) is a non-functional, processed pseudogene related to the active SLC39A14 gene, which encodes a metal ion transporter. Pseudogenes like this are DNA segments similar to known genes but lack the ability to produce a functional protein, typically due to mutations or the absence of regulatory elements. They are generally considered non-coding and are not therapeutic targets, though in rare cases some pseudogenes may participate in gene regulation at the RNA level[2][4][6]. Note: - The functional protein-coding gene SLC39A14 (ZIP14) is involved in metal ion transport (manganese, zinc, iron) and is a genuine transporter protein with clinical significance, but this is distinct from the pseudogene ENSG00000227236[1][3][7]. - Any therapeutic, biomarker, or mechanistic information applies only to the functional gene, not to this pseudogene. This entry should not be used as a therapeutic target in any structured database or resource.
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