Target intelligence / Profile preview

Solute carrier family 45 member 3 (P501S)

Target
P501S
Molecular classification
Membrane protein, Transporter
01

Overview

Prostein, also known as P501S or SLC45A3, is a prostate-specific membrane protein highly specific for both benign and malignant prostatic epithelial cells. It is used in pathology to identify tissue of prostatic origin. While not a direct drug target, its expression is androgen-responsive, making it relevant to understanding prostate cancer progression and therapy response. It is predominantly localized in the Golgi complex.

Other names
ProsteinSLC45A3Prostate cancer-associated protein 6IPCA-2IPCA-6IPCA-8PCANAP2PCANAP6PCANAP8PRST
02

Biological functions

TransportAndrogen-responsive activity
03

Disease associations

Prostate cancerCancer biomarker
04

Biomarkers

Prostate cancer diagnosisProstate cancer prognosis

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