Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Solute carrier family 66 member 2 (SLC66A2)
- Target
- SLC66A2
- Molecular classification
- Transporter
01
Overview
Solute carrier family 66 member 2 (SLC66A2) is a predicted membrane transporter protein belonging to the solute carrier (SLC) superfamily, specifically classified within the SLC66 family[9]. The protein is thought to participate in phospholipid translocation and retrograde transport, moving molecules from the endosome to the Golgi network[1][4]. SLC66A2 is localized to membrane compartments, including the cytosol, endosome, and trans-Golgi network[1][4]. While biochemical evidence supports transporter activity for some SLC66 family members, SLC66A2's precise substrate specificity and physiological function remain incompletely characterized[9]. The gene is protein-coding and is associated with certain rare diseases and various normal tissue expressions, but it is not a well-established therapeutic target with approved drugs or demonstrated disease-modifying drugs to date[4][9].
- Other names
- SLC66A2PQLC1FLJ22378PQ-loop repeat-containing protein 1PQ loop repeat containing 1
02
Biological functions
Phospholipid translocationRetrograde transport (endosome to Golgi)Potential transporter of molecules across membranes
03
Disease associations
Cancer (based on associations in expression/tissue datasets[1][4])Other (evidence links to wider disease mechanisms, e.g., involvement in gene-disease association datasets including Schwartz-Jampel Syndrome, Cerebral Arteriopathy[4])
Beyond the preview
Go deeper on Solute carrier family 66 member 2 (SLC66A2).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Solute carrier family 66 member 2 (SLC66A2).