Solute carrier family 9 member B1 pseudogene 3 (SLC9B1P3)

SLC9B1P3 encodes a pseudogene related to the solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1. Unlike functional SLC9B transporters (such as SLC9B1/NHA1 and SLC9B2/NHA2), which mediate sodium/proton exchange and are involved in ion homeostasis, SLC9B1P3 is not translated into a functional protein. Pseudogenes like SLC9B1P3 may arise by gene duplication or retrotransposition and often contain sequence similarity to their functional counterparts but lack protein-coding ability due to mutations, frame shifts, or absence of essential regulatory elements. There is no established biological function, disease association, or pharmacological interaction for SLC9B1P3. Its nomenclature is easily confusable with active transporter proteins, so care must be taken not to mistake this pseudogene for a protein-coding member (e.g., SLC9B1/NHA1)[7][6].

Other names

Solute Carrier Family 9 Member B1 Pseudogene 3Solute Carrier Family 9, Subfamily B (NHA1, Cation Proton Antiporter 1), Member 1 Pseudogene 3Na^+/H^+ Exchanger Domain Containing 1 Pseudogene 3Solute Carrier Family 9, Subfamily B (Cation Proton Antiporter 2), Member 1 Pseudogene 3NHEDC1P3Putative SLC9B1-like Protein SLC9B1P3