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SORCS3 antisense RNA 1 (SORCS3-AS1)

Target
SORCS3-AS1
Molecular classification
antisense long non-coding RNA, lncRNA
01

Overview

SORCS3 antisense RNA 1 (SORCS3-AS1) is an intragenic, non-protein-coding RNA gene transcribed antisense to the SORCS3 protein-coding locus on chromosome 10. It is classified as an antisense lncRNA with strong evidence for non-coding status (PhyloCSF, CPAT, Bazzini, PRIDE)[1]. There is no published literature or direct functional characterization of SORCS3-AS1. Alternative transcript names and accessions exist across major databases (NCBI, Ensembl, NONCODE), but its molecular function, disease relevance, and biological mechanisms remain unexplored. SORCS3-AS1 is distinct from SORCS3, which encodes a receptor protein involved in neuronal signaling and disease[3][7][9]. Summary of distinctions: - SORCS3-AS1 is an antisense lncRNA, not a protein, receptor, or enzyme[1][6][8]. - No disease, drug, or biomarker association is reported for SORCS3-AS1[1][2][6][8]. - Most available literature and disease associations concern SORCS3, not SORCS3-AS1[3][7][9]. All major databases (NCBI, Ensembl, LNCipedia, BioGPS, Thermo Fisher) corroborate the existence and sequence information of SORCS3-AS1, but do not provide functional or therapeutic relevance[1][2][5][6][8].

Other names
SORCS3-AS1ENSG00000226387NR_104028.1AK097854.1BU852305.1NONHSAT016242SORCS3 antisense RNA 1
02

Biological functions

currently unknowntypical lncRNAs can regulate gene expressionchromatin structureRNA stabilityplay epigenetic roles
03

Disease associations

no confirmed disease associationsgenetic loci sometimes show copy number variation gains or losses co-localized with SORCS3, but functional or disease involvement is not established

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