Target intelligence / Profile preview

Sorting nexin 29 pseudogene 2 (SNX29P2)

Target
SNX29P2
Molecular classification
Other (Pseudogene)
01

Overview

Sorting nexin 29 pseudogene 2 is a pseudogene found in humans on chromosome 16p11.2. It is annotated as a non-protein-coding locus and is not considered to encode a functional protein. The gene has been referred to as RUN domain-containing protein 2C and Putative protein SNX29P2, but there is no evidence that these aliases reflect a protein product in vivo.[2][5][6] Pseudogenes like SNX29P2 typically arise from duplication or retrotransposition events of protein-coding genes (in this case, Sorting nexin 29), but accumulate mutations that render them non-functional. As a pseudogene, SNX29P2 is not a therapeutic target, does not encode a receptor, enzyme, or other druggable entity, and has no known biological or disease-modifying function. No associated drugs, mechanisms of action, biomarkers, or safety concerns are documented. The molecule should not be considered a valid target for drug discovery or therapeutic intervention, and reporting as a drug target is incorrect.[2][5][6]

Other names
SNX29P2RUNDC2CPutative protein SNX29P2RUN domain-containing protein 2CSorting nexin 29 protein pseudogene 2
02

Biological functions

No confirmed function; pseudogene
03

Disease associations

No validated role in disease; sometimes pseudogenes can be implicated but no data for SNX29P2

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