Sosondowah ankyrin repeat domain family member C (SOWAHC)

Sosondowah ankyrin repeat domain family member C (SOWAHC) is a human protein containing ankyrin repeat domains, a structural motif that facilitates protein–protein interactions and is present in proteins regulating transcription, cell cycle, and cytoskeletal organization. SOWAHC has been identified as a methylation-driven gene in lung squamous cell carcinoma, with hypomethylation and high expression correlating with poor prognosis, suggesting its involvement in regulating transcriptional networks and gene expression relevant to cancer progression. The protein belongs to the ankyrin repeat family but is not classified as a canonical receptor, enzyme, or transporter; its primary function appears to be nuclear regulation rather than cell surface signaling. Predicted protein interactors suggest possible involvement in cytoskeletal processes, but direct functional characterizations are limited. No drugs directly target SOWAHC, and there is no reported involvement in adverse effects or contraindications.

Other names

ANKRD57C2orf26FLJ21870Ankyrin repeat domain-containing protein 57Protein sosondowah homolog C

Not applicable. No clinically approved drugs or mechanisms of drug action have been described for SOWAHC.