Spermatogenesis-associated protein 21 (SPATA21)

Spermatogenesis-associated protein 21 (SPATA21) is a protein encoded by the SPATA21 gene in humans that is involved in the differentiation of haploid spermatids during the process of spermatogenesis[1][3]. It is classified as a calmodulin-related protein and is predicted to enable calcium ion binding activity[3][4][7][8][10]. Currently, SPATA21 is not recognized as a therapeutic target (e.g., receptor, enzyme, channel, or transporter), and there are no known interacting drugs or commonly used biomarkers in clinical practice. Its function is specific to testicular tissue related to male fertility, although it may appear in broader gene expression analyses such as cancer datasets; however, there are no validated disease associations or therapeutic risks described in public databases[6]. If further details about classification, drug interactions, or disease mechanisms become available in the future, they may alter its status as a possible therapeutic or diagnostic target.

Other names

spergen-2spergen2spermatogenesis associated 21SPT21