Spider Venom Components (N/A)

Spider venom is a complex mixture of bioactive molecules, including small molecular mass compounds, antimicrobial peptides, cysteine-rich peptide neurotoxins, and proteins/enzymes like phospholipases and proteases. These components target neuronal or neuromuscular signal transduction systems, with key targets including voltage-gated ion channels (NaV, CaV, KCa), lipid bilayers, and NMDA receptors. Venom components exhibit diverse biological activities, such as neurotoxic effects, antimicrobial properties, and insect-selective toxicity. Many spider venom peptides display potent pharmacological activities, rendering them valuable resources for potential therapeutic candidates.

Other names

Spider venom toxinsSpider venom peptidesSpider venom enzymesSpider venom neurotoxins

Modulation of ion channel gating, disruption of membrane integrity, enzymatic degradation of phospholipids and extracellular matrix, receptor binding