Spindlin family member 2B (SPIN2B)

Spindlin family member 2B (SPIN2B) is a protein encoded by the SPIN2B gene located on chromosome X in humans[2]. It belongs to the spindlin family, characterized by Spin/Ssty repeats, which are around 50 amino acids long and likely form independent functional units within the protein structure[1]. SPIN2B's function is partially defined—it is involved in the regulation of cell cycle progression and has a role relating to the inhibition of apoptosis after growth factor withdrawal[4][6]. The protein is also predicted to bind methylated histones and may be involved in controlling DNA-templated transcription[3]. Experimental data suggest spindlin family proteins play important roles during meiosis, mitosis, and early embryogenesis, but comprehensive biochemical functions and disease associations are largely uncharacterized[1]. There are no known drugs, clinical biomarkers, or established safety challenges linked to this protein[4][6].

Other names

Spindlin-2BSPIN2SPIN-2TDRD26Spindlin-like protein 2BdJ323P24.2Telomeric SPIN2 copySPIN2_duplicateSpindlin family, member 2 duplicate