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Spleen and stomach qi, in Traditional Chinese Medicine, refers to the vital functional energy produced by the spleen and stomach working together. It underpins digestion, absorption of nutrients and fluids, transformation of food into usable energy (qi) and blood, and is considered essential for overall physical vitality, muscle strength, cognitive function, and immune resilience. While various herbal and dietary therapies are prescribed in TCM to "strengthen spleen and stomach qi," there is no anatomical correlate or scientific "receptor" known by this name; rather, it is a symbolic construct denoting healthy digestive and systemic function[1][2][3][5]. In modern biomedical terms, "spleen and stomach qi" should not be treated as a molecular, protein, or cell-surface target, receptor, or any other standard therapeutic target category. It remains exclusively within the theoretical framework of TCM and holistic traditional health systems[1][2][5][6].
TCM herbal medicine is said to "tonify," "nourish," or "strengthen" spleen and stomach qi, improving digestion, energy, and blood according to traditional concepts. Mechanistic parallels in modern research (such as increased amylase, changes in hormone secretion) are proposed but not biochemically standardized[2][5].
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