Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Spleen and Stomach Qi Tonification is a fundamental therapeutic principle in Traditional Chinese Medicine (TCM) rather than a specific molecular target, receptor, or enzyme. In the context of TCM theory, the Spleen and Stomach are the primary functional units responsible for the digestion of food and the subsequent extraction and distribution of nutrients to form Qi (vital energy) and blood (Wiseman & Ellis, 1996). A deficiency in this system, known as Spleen Qi Deficiency, is clinically characterized by symptoms such as chronic fatigue, poor appetite, loose stools, and muscle wasting (Maciocia, 2015). Treatment strategies for this condition utilize specific herbal formulas, most notably Buzhong Yiqi Tang, which aim to restore the "ascending" function of the Spleen and the "descending" function of the Stomach (Chen & Chen, 2004). While modern pharmacological studies have investigated the effects of these herbs on mitochondrial function, gastrointestinal motility, and immune modulation, the term itself describes a holistic physiological state and clinical objective rather than a single protein or gene target (Zhao et al., 2015). Consequently, it does not possess a canonical molecular classification or a single mechanism of action in the Western pharmacological sense.
In Traditional Chinese Medicine, this principle involves the use of tonifying herbs to enhance the "transformation and transportation" functions of the digestive system, thereby increasing the production of vital energy (Qi) and improving systemic metabolic function.
4 more in the full profile.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Explore the programs pursuing this target and their development progress.
Follow the clinical studies evaluating therapies directed at this target.
Compare approaches across drug candidates, modalities, and indications.
Investigate the research and source evidence behind target biology and development.
Explore patent activity around therapies and technologies addressing this target.
Connect target biology, drug development, and emerging evidence in your research.
See how Gosset can support your research on Spleen and Stomach Qi Tonification.