Spleen function regulation via multi-herb synergy according to TCM theory

Spleen function regulation via multi-herb synergy according to TCM theory" refers to a holistic concept in Traditional Chinese Medicine whereby the function of the 'spleen'—understood as a central organ-system in digestion, energy production, nutrient distribution, immune regulation, and water metabolism—is modulated through combinations of herbal medicines. Unlike biomedical targets defined at the molecular level (e.g., receptors or enzymes), this is a systems-level therapeutic concept. TCM 'herb synergy' describes using prescriptive combinations of herbs aimed at restoring or supporting physiological harmony, with the spleen being treated as a pivotal organ for nutrient assimilation and immune function. While modern studies have characterized some biochemical and physiological correlates—such as improved gut barrier integrity, knowledge of immune modulation, and gut microbiome effects—these findings do not map to a single protein or druggable target, and instead support the broader TCM organ-function-multitarget paradigm.

Other names

Regulation of spleen functionSpleen function modulation in TCMSpleen qi regulationMulti-herb synergy in spleen function

Multimodal and systemic (regulation of intestinal mucosa, immune modulation, modulation of gut flora, improvement of digestion, anti-inflammatory, etc.); Not attributable to a single molecular pathway