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Spleen-stomach yang deficiency syndrome is a diagnostic pattern in Traditional Chinese Medicine (TCM), referring to insufficient "yang" (warming and energizing function) of the spleen and stomach, resulting in coldness and hypoactivity in digestive and metabolic functions. Main symptoms include abdominal pain, poor appetite, loose stools or diarrhea, a pale tongue with white coating, fatigue, cold limbs, and a weak pulse. In TCM, the spleen and stomach jointly manage transformation and transportation of nutrients; their yang deficiency is linked to 'internal cold,' dampness, and systemic sluggishness. This syndrome does not correspond to a single molecular or protein-based target recognized in modern pharmacology or molecular medicine. This entry cannot be reliably mapped to any gene, receptor, enzyme, transporter, or other canonical biomedical target. It represents a clinical pattern from traditional medical theory, not a discrete molecular entity or protein target.
Not applicable (formulas are prescribed based on theoretical restoration of "yang" and digestion; not molecular targeting)
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