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Target intelligence / Profile preview
Src proto-oncogene tyrosine-protein kinase (Src)
- Target
- Src
- Molecular classification
- Enzyme, Non-receptor tyrosine kinase, Src family kinase
01
Overview
Src proto-oncogene tyrosine-protein kinase is a central non-receptor protein tyrosine kinase regulating diverse biological processes via phosphorylation signaling networks. Its dysregulation contributes significantly to oncogenesis making it an important therapeutic target especially within oncology research pipelines.
- Other names
- pp60c-srcTyrosine kinase pp60(src)SRC1Pp60(src)P60-SrcC-src TK
02
Mechanism of action
Tyrosine kinase inhibition
03
Biological functions
Signal transductionCell growth regulationEmbryonic developmentImmune responseCell adhesionCell migrationCytoskeletal organizationApoptosis
04
Disease associations
CancerColon cancerBreast cancerMyeloproliferative neoplasmsIschemia-related pathologies
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