SRP14 divergent transcript (SRP14-DT)

SRP14 divergent transcript (SRP14-DT) is a human long non-coding RNA (lncRNA) gene located on chromosome 15, with multiple splice variants. It is widely listed in gene annotation databases, such as Ensembl and GeneCards, with alternative names like SRP14-AS1 and SRP14 antisense RNA1 (head to head). Its expression has been reported in regions including the cervical spinal cord and amygdala, and there is evidence for a role within the immune system, particularly in the lung. Functionally, SRP14-DT does not encode a protein and is distinct from the protein-coding gene SRP14. Disease relevance is limited, with some associations noted for aortic aneurysm (familial thoracic type 1), but there is no confirmed link as a therapeutic target or receptor, nor are there approved drugs or safety concerns documented in major biomedical databases.

Other names

SRP14-AS1SRP14 antisense RNA1 (head to head)