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SRPK2 pseudogene 1 (SRPK2P1) is a non-coding pseudogene related to the protein kinase gene SRSF protein kinase 2 (SRPK2). Unlike the coding gene SRPK2, which is a serine/threonine kinase involved in splicing regulation, actin cytoskeleton remodeling, and cancer progression, SRPK2P1 does not encode a functional protein and is not considered a therapeutic target or of direct biological, disease, or drug relevance[1][2][3]. The nomenclature confusion arises because studies and databases focus on SRPK2, not on its pseudogene variants; SRPK2P1 itself lacks functional or clinical significance. SRPK2P1 (the pseudogene) is not a drug target, receptor, enzyme, transporter, or involved in disease processes. SRPK2 (the protein-coding gene) is an enzyme implicated in cancer and cell signaling, and is the actual therapeutic target in research settings[1][2][3].
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