Target intelligence / Profile preview

SSU72 like 2 (SSU72L2)

Target
SSU72L2
Molecular classification
Pseudogene, Uncharacterized gene locus
01

Overview

There is no evidence that "SSU72 like 2" (SSU72L2, SSU72P2) encodes a functional protein or serves as a valid molecular target. The SSU72 gene encodes an evolutionarily conserved phosphatase involved in regulating the phosphorylation state of RNA polymerase II C-terminal domain (CTD), but "SSU72L2" appears to denote a pseudogene or uncharacterized gene locus without demonstrated protein product or biological function in humans. No information supporting its role as a therapeutic target, molecular receptor, or functional biomolecule is found in current scientific literature or authoritative biological databases. The only characterized, functionally validated entity in this family is the SSU72 phosphatase[1][2][3]. Key points: - **SSU72L2 (SSU72 like 2)** is likely a *pseudogene* or uncharacterized gene locus, not a validated protein or target. - The *true functional protein* in this family is SSU72, an RNA polymerase II CTD phosphatase essential for transcription regulation and 3’ RNA processing[1][2][3]. - No evidence exists for SSU72L2 being a receptor, enzyme, transporter, or established drug target. - There are no known drugs, biomarkers, disease associations, or safety concerns relevant to SSU72L2. In summary, SSU72L2 is not a functional therapeutic target. The entry likely results from confusion with the canonical SSU72 phosphatase, which is both well-studied and functional, but no such characterization exists for SSU72L2[3].

Other names
SSU72 like 2SSU72L2RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 2SSU72P2CTD phosphatase SSU72L2SSU72 RNA polymerase II CTD phosphatase homolog pseudogene 2SSU72 pseudogene 2
02

Biological functions

No known biological function in humans (likely a pseudogene)
03

Disease associations

No known disease roles

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