ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 pseudogene 1 (ST6GALNAC4P1)

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 pseudogene 1 (ST6GALNAC4P1) is a human pseudogene that shares sequence similarity with the functional ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (ST6GALNAC4) gene, which encodes an enzyme involved in sialylation of glycoproteins and glycolipids. As a pseudogene, ST6GALNAC4P1 is not known to encode a functional protein and is not considered a therapeutic target. While some pseudogenes can regulate gene expression or be implicated in genetic disorders through gene conversion, RNA interference, or serving as mutation “decoys,” there is no evidence for such activity with this specific pseudogene. However, like other pseudogenes, its high sequence similarity to its functional parent can pose challenges for genetic testing such as sequencing read misalignment, which may cause diagnostic errors. There are no known drugs, mechanisms, or biomarkers associated specifically with ST6GALNAC4P1.

Other names

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 pseudogene 1ST6 GalNAc alpha-2,6-sialyltransferase 4 pseudogene 1ST6GALNAC4P1