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Target intelligence / Profile preview
Stabilizer of axonemal microtubules 2 (SAXO2)
- Target
- SAXO2
- Molecular classification
- Other (microtubule-associated protein)
01
Overview
Stabilizer of axonemal microtubules 2 (SAXO2) is a protein encoded by the SAXO2 gene in humans. It is predicted to enable microtubule binding activity and is believed to function in the cytoskeleton, particularly within microtubules, the nucleus, and sperm flagellum. Although it belongs to a family of proteins associated with cilia and axonemal structures (related to the movement and stability of cilia and flagella), its precise biological functions remain incompletely characterized. SAXO2 has been linked to genetic conditions such as autosomal dominant deafness (type 68) and otosclerosis 1. Current evidence does not suggest SAXO2 is a direct therapeutic target, nor are there known drugs targeting it or specific biomarkers for clinical selection.
- Other names
- FAM154BDKFZp666G057Family with sequence similarity 154, member BProtein FAM154B
02
Biological functions
Microtubule bindingcytoskeleton organizationpredicted activity in cilia and flagellar structures
03
Disease associations
Deafness, Autosomal Dominant 68Otosclerosis 1
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