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Target intelligence / Profile preview
Staphylococcus aureus (S. aureus)
- Target
- S. aureus
- Molecular classification
- Bacterium, Gram-positive bacterium, Pathogen
01
Overview
Staphylococcus aureus is a gram-positive bacterium commonly found on the skin and in the nose of humans. It is an opportunistic pathogen capable of causing a wide range of infections, from minor skin conditions to life-threatening systemic diseases. Its high propensity for developing antibiotic resistance, particularly methicillin resistance (MRSA), poses a significant clinical challenge. S. aureus produces numerous virulence factors and employs sophisticated immune evasion strategies, contributing to its pathogenicity and persistence. No vaccine is currently available.
02
Mechanism of action
N/A - target is an organism, not a specific molecule. Antibiotics target various bacterial processes (cell wall synthesis, protein synthesis, etc.)
03
Biological functions
ColonizationInfectionImmune evasionAntibiotic resistance development
04
Disease associations
Skin infectionsPneumoniaMeningitisOsteomyelitisEndocarditisToxic shock syndrome (TSS)BacteremiaSepsisHospital-acquired infections
05
Safety considerations
Antibiotic resistanceMethicillin-resistant Staphylococcus aureus (MRSA)Multidrug-resistant strainsHigh mortality rate associated with severe infectionsLack of effective vaccine
06
Interacting drugs
Methicillin
1 more in the full profile.
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