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Target intelligence / Profile preview
Staphylococcus aureus capsular polysaccharide serotype 5 (CP5)
- Target
- CP5
- Molecular classification
- Polysaccharide, Carbohydrate, Capsular Polysaccharide
01
Overview
Staphylococcus aureus capsular polysaccharide serotype 5 (CP5) is a high-molecular-weight carbohydrate polymer that forms a capsule on the surface of S. aureus bacteria. It is a major virulence factor, enabling immune evasion by inhibiting phagocytosis and reducing complement binding. CP5 is a prevalent serotype among clinical isolates and a target for vaccine development.
- Other names
- S. aureus capsular polysaccharide serotype 5Capsular polysaccharide serotype 5Staphylococcus aureus CP5
02
Mechanism of action
Target of vaccine development to elicit antibody-mediated opsonization and phagocytosis
03
Biological functions
Immune evasionAntiphagocytosisVirulence factorCapsule formation
04
Disease associations
InfectionBacteremiaAbscess formationArthritis
05
Safety considerations
Limited antigenic diversity may require combination vaccine approaches
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