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Target intelligence / Profile preview
Staphylococcus aureus capsular polysaccharide type 5 (None)
- Target
- None
- Molecular classification
- Polysaccharide, Capsular Polysaccharide, Virulence Factor
01
Overview
Staphylococcus aureus capsular polysaccharide type 5 (CP5) is a high-molecular-weight carbohydrate polymer that forms the bacterial capsule, a key virulence factor. It promotes immune evasion by inhibiting opsonophagocytosis and modulates adhesion. It also stimulates cytokine production in human cells. As a major serotype in clinical isolates, it is a potential target for vaccine development.
- Other names
- CP5CP Type 5CPV
02
Mechanism of action
Antibodies against CP5 promote phagocytosis
03
Biological functions
Immune evasionAdhesion modulationProtection from opsonophagocytic killingVirulenceCytokine induction
04
Disease associations
Staphylococcus aureus infectionBacteremia
05
Safety considerations
Potential for immune response modulation
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