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This target is a pseudogene for the Staufen family of double-stranded RNA-binding proteins. Pseudogenes are DNA sequences similar to known genes but are generally non-functional; they usually arise from duplication or retrotransposition and do not produce functional proteins. While the STAU1 protein has important cellular roles in mRNA localization, stability, decay, and viral replication, the pseudogene designated ENSG00000269765 does not encode these activities and is not an actionable target for therapeutic intervention[2][3].
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