Target intelligence / Profile preview

Sterile alpha motif domain-containing protein 10 (SAMD10)

Target
SAMD10
Molecular classification
Other (SAM domain-containing protein), Scaffold protein (inferred from SAM domain context[2][3][5])
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Overview

Sterile alpha motif domain-containing protein 10 (SAMD10) is a human protein encoded by the SAMD10 gene. It contains a sterile alpha motif (SAM) domain, which is a protein-protein interaction module found in many eukaryotic proteins, typically facilitating the assembly of multiprotein complexes through oligomerization or scaffolding roles[1][2][3][5]. While the SAM domain itself is associated with various functions such as signal transduction, transcription regulation, and RNA binding in other proteins, the specific biological role of SAMD10 remains inadequately characterized in reviewed sources. SAMD10 is not currently established as a pharmacological or therapeutic target, has no known association with disease, and no drugs nor biomarkers target this protein. Its molecular function is presumed to involve structural or regulatory assembly of proteins, analogous to other SAM domain-containing members[1][2][3][5].

Other names
SAMD10Sterile alpha motif domain-containing protein 10
02

Mechanism of action

Not applicable (no drugs identified as targeting SAMD10).

03

Biological functions

Protein-protein interaction module (SAM domain mediates homo-/hetero-oligomerization)Possibly scaffolding for multi-protein complex formation, by analogy to other SAM domain proteinsSpecific functions for SAMD10 remain uncharacterized as of current literature
04

Disease associations

None specifically characterized for SAMD10. No links found to cancer, inflammation, neurodegeneration, cardiovascular disease, infection, or other diseasesOther SAM domain proteins may participate in disease processes[3], but no explicit evidence for SAMD10.
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Safety considerations

None described; no notable safety concerns or therapeutic challenges currently relevant
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Interacting drugs

None identified. No drugs are currently described to interact with SAMD10.
07

Biomarkers

None identified for patient selection or efficacy monitoring

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