Stimulation of colonic motility

"Stimulation of colonic motility" describes enhanced contractile or motor activity in the colon, usually as a result of activation of enteric neural circuits, smooth muscle, or specific receptors, which leads to increased movement of contents through the large intestine. This is a physiological process regulated by multiple molecular entities (e.g., neurotransmitter receptors, ion channels, signaling proteins), but in itself is not the name of a molecular target, gene, or protein. The phrase refers to an effect or outcome, not to a druggable target such as a receptor, enzyme, or channel. It is a collective outcome resulting from modulation of several molecular and cellular pathways in the colon. For structured data, specific molecular targets (e.g., 5-hydroxytryptamine receptor 4, Muscarinic acetylcholine receptor M3, Motilin receptor) should be specified if molecular information is required.

Other names

enhanced colonic motilitycolonic motor stimulationincreased colonic peristalsis