Target intelligence / Profile preview

STK32A antisense RNA 1 (STK32A-AS1)

Target
STK32A-AS1
Molecular classification
Long non-coding RNA, Antisense RNA
01

Overview

STK32A antisense RNA 1 (STK32A-AS1) is a long non-coding RNA gene located at the STK32A locus on the human genome. It functions to regulate the expression of the STK32A coding gene, both by targeting enhancer and promoter regions, and likely acts in cis to positively modulate STK32A gene expression [8]. There is currently no evidence that STK32A-AS1 acts as a therapeutic target, nor is it implicated in specific diseases or known to interact with any drugs [2][4][8]. While other antisense lncRNAs are involved in disease biology, STK32A-AS1's biological and disease relevance is presently unclear and its functional description is limited primarily to gene expression regulation at the chromatin level.

Other names
CTC-255N20NR_147190.1
02

Mechanism of action

Not applicable. No drugs or therapeutic modalities target this RNA directly.

03

Biological functions

Regulation of gene expression (by targeting enhancer and promoter regions of STK32A and modulating its expression)
04

Disease associations

No direct disease association is documented yet for STK32A-AS1. No evidence for involvement in cancer, neurodegeneration, or other diseases was found
05

Safety considerations

None known. There are no therapeutics or interventions targeting STK32A-AS1, and thus no safety concerns are discussed
06

Interacting drugs

None known. No drugs are documented to interact specifically with STK32A-AS1.
07

Biomarkers

None documented for patient selection or monitoring. No clinical utility is described

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