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Stomach fire

Molecular classification
Other (TCM pattern; not a molecule, gene, receptor, or protein)
01

Overview

Stomach fire (also known as Stomach heat) is a diagnostic pattern in Traditional Chinese Medicine denoting an excess of heat (fire) in the Stomach system, often associated with symptoms such as dry mouth, intense thirst, preference for cold drinks, bad breath, gum swelling or pain, mouth ulcers, constipation, yellow tongue coating, and rapid, slippery pulse[1][5][6][7].\nIt is commonly attributed to dietary factors (excessively spicy, greasy, or fried foods), emotional stress, or internal imbalances such as hyperactivity of Liver or Heart fire invading the Stomach[1][3][4].\n"Multi-herb synergy" reflects the TCM approach of treating this pattern with complex herbal combinations, such as Qing Wei San, Bai Hu Tang, or Tiao Wei Cheng Qi Tang, designed to clear heat/fire, cool the blood, and restore balance[1][2][7].\nAlthough these patterns can guide herbal and acupuncture treatment in TCM practice, they do not correspond to a molecular entity or therapeutic target defined by Western medicine, pharmacology, or biotechnology.

Other names
Stomach heatStomach fireWei Re (胃热)Wei Huo (胃火)Stomach Heat syndromeStomach Fire syndrome
02

Mechanism of action

Clearing heat/fire (cooling), nourishing Yin, descending Stomach Qi, harmonizing Stomach system; these are TCM conceptual mechanisms—not molecular interactions

03

Biological functions

Other (TCM describes it functionally as heat excess in the Stomach system causing symptoms like thirst, gum swelling, dry mouth, bad breath, etc.)
04

Disease associations

Other (TCM context: described as linked to gastric discomfort, peptic ulcer, chronic gastritis, gingivitis, diabetes type II, toothache, stomach cancer, esophageal cancer, and other disorders on a symptomatic, not mechanistic, basis)
05

Safety considerations

Vague—potential for misdiagnosis if used in place of modern medicine; herb-drug interactions and side effects possible depending on herb combination, but not usually addressed in TCM literature
06

Interacting drugs

Chinese herbal formulas such as Qing Wei San, Tiao Wei Cheng Qi Tang, Bai Hu Tang, Da Chaihu Tang; these are multi-herb mixtures and not single drugs
07

Biomarkers

None established (there are no molecular biomarkers; TCM uses symptom patterns like red tongue, rapid/strong pulse, dry mouth, etc.)

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