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The **Stomach meridian** is a conceptual "energy channel" described in Traditional Chinese Medicine (TCM), running from just below the eye, down the face, through the chest and abdomen, and along the front of the leg to the top of the foot[1][7]. It is understood in TCM to govern the **initial stage of digestion**, as well as the *transformation and movement of nutrients and fluids*. The Stomach meridian is paired with the *Spleen meridian* and together they are said to form the central axis of digestion and nourishment in the body[3][5]. In TCM, imbalances in this meridian are believed to manifest both as physical symptoms (digestion-related discomfort, muscular issues along its pathway) and as emotional problems, especially worry or overthinking[1][7]. The meridian system (including the Stomach meridian) is a pseudoscientific concept not supported by anatomical or biochemical evidence in modern biomedical science[9]. **Critical note:** - The **Stomach meridian is not a defined molecular target, receptor, enzyme, transporter, or measurable biomolecule**. - It does not have a canonical abbreviation recognized in pharmacology or molecular biology. - The term and concept are specific to Traditional Chinese Medicine and are not used in evidence-based medicine; its existence is not supported by scientific evidence[9]. - No drugs or mechanisms of action directly target the Stomach meridian as such. - There are no known biomarkers or safety considerations, as it is not a biomedical entity. This entry is considered "incorrect" by the standards of pharmacological or molecular target annotation because it refers to a pre-modern, non-molecular, traditional medical concept rather than a discrete biological molecule, molecular pathway, or true drug target[9].
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