Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Stratum Corneum Lipid Bilayer (SC Lipid Bilayer)
- Target
- SC Lipid Bilayer
- Molecular classification
- Lipid matrix, Extracellular matrix component
01
Overview
The stratum corneum lipid bilayer is a specialized, multi-lamellar structure in the outermost skin layer. It forms a continuous matrix around corneocytes, composed primarily of ceramides, free fatty acids, and cholesterol. This lipid matrix is crucial for the skin’s barrier function, preventing water loss and protecting against external threats. Its unique composition and organization, featuring small hydrophilic head groups, variable alkyl tail lengths, and extensive hydrogen bonding, distinguish it from other biological membranes. Disruptions in the lipid composition or structure can lead to various skin disorders.
02
Biological functions
Permeability barrierPrevention of desiccationProtection against pathogens and toxins
03
Disease associations
PsoriasisIchthyosisSkin barrier dysfunction
04
Safety considerations
Disruption can lead to increased permeability to harmful substancesImbalances can compromise skin function
05
Biomarkers
Ceramide levelsFree fatty acid levelsCholesterol levels
Beyond the preview
Go deeper on Stratum Corneum Lipid Bilayer (SC Lipid Bilayer).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Stratum Corneum Lipid Bilayer (SC Lipid Bilayer).