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Target intelligence / Profile preview
Streptococcus pneumoniae Protein Antigen SP1912 (SP1912)
- Target
- SP1912
- Molecular classification
- Protein, Antigen
01
Overview
SP1912 is a conserved protein antigen found in *Streptococcus pneumoniae*. It is a promising candidate for inclusion in pneumococcal protein-based vaccines due to its universal presence across global pneumococcal populations and its ability to elicit immune responses. While its precise biological function remains unknown, it is a highly conserved, immunodominant antigen, suggesting an essential role for bacterial physiology. It induces T cell responses, particularly Th17-type immunity, important for protection against colonization and invasive disease.
- Other names
- sp_1912 (TIGR4)Nonlipidated pneumococcal proteinHypothetical protein SP1912Uncharacterized protein SP1912
02
Mechanism of action
Induction of T cell (Th17) mediated immunity
03
Biological functions
Immune responseBacterial physiology (hypothetical)
04
Disease associations
InfectionPneumococcal disease
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