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Streptococcus pneumoniae Type 1 Capsular Polysaccharide Antigen
- Molecular classification
- Bacterial Capsular Polysaccharides, Vaccines, Antigen
01
Overview
The Streptococcus pneumoniae type 1 capsular polysaccharide antigen is a highly purified carbohydrate antigen derived from the capsule of *Streptococcus pneumoniae* serotype 1. This molecule is a key component in certain pneumococcal vaccines, where it serves as an immunogen to induce protective immunity against infections caused by this serotype. The capsular polysaccharide acts as a major virulence factor, protecting the bacterium from phagocytosis. It induces actively acquired immunity and activates both B-cells and CD4+ T-cells.
- Other names
- H9NOI61UH1Streptococcus pneumoniae Type 1 Polysaccharide Antigen, APneumococcal capsular polysaccharide type 1 vaccinePNEUMOCOCCAL POLYSACCHARIDE SEROTYPE 1
02
Mechanism of action
Induces actively acquired immunity by stimulating B-cell and CD4+ T-cell responses, leading to the production of antibodies against Streptococcus pneumoniae serotype 1.
03
Biological functions
Immune responseVirulence factorAntigen presentationProtection against phagocytosis
04
Disease associations
InfectionPneumococcal pneumoniaBacteremiaInvasive pneumococcal disease
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