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Target intelligence / Profile preview
Streptococcus pneumoniae type 6B capsular polysaccharide antigen (CPS 6B)
- Target
- CPS 6B
- Molecular classification
- Polysaccharide, Antigen, Vaccine component
01
Overview
The Streptococcus pneumoniae type 6B capsular polysaccharide antigen is a purified carbohydrate component from the capsule of the S. pneumoniae serotype 6B. It is used in vaccines to elicit a serotype-specific immune response, primarily through the production of opsonizing antibodies, leading to protection against invasive pneumococcal disease.
- Other names
- Pneumococcal serotype 6B capsular polysaccharideS. pneumoniae 6B CPSType 6B CPS
02
Mechanism of action
Induction of opsonizing antibodies against Streptococcus pneumoniae serotype 6B, leading to enhanced phagocytosis and complement-mediated killing of the bacteria.
03
Biological functions
Immune response inductionAntibody productionOpsonizationComplement activationB cell activation
04
Disease associations
Pneumococcal pneumoniaBacteremiaInfection
05
Safety considerations
Injection site reactionsFeverAllergic reactions (rare)Guillain-Barré syndrome (rare)
06
Interacting drugs
Prevnar13
3 more in the full profile.
07
Biomarkers
Anti-capsular antibody titers (IgG)Serotype-specific IgG concentrationOpsonophagocytic activity (OPA) assay
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